Ok I checked with Leisa and since she works for surgeons she personally hasn't prescribed either of these but she looked both up on drug reference app. She said first of all she wouldn't recommend they start both of these at the same time and she didn't like Zyprexa at all. She said that she sees a lot of elderly patients on Remeron and thought it would help him sleep. S bottom line is that of the two Remeron would be the starting place I think. Hope this helps some but nit working for a GP limits the drugs Leisa is most familiar with. Love to all, Judy